Company
Elysium Health
Last updated 2026-05-17· 1 min read
Reviewed by the Ultimate Longevity Bible editorial team. Educational reference — not medical advice. See disclaimer.
What it is
Elysium Health is a direct-to-consumer supplement brand co-founded by Leonard Guarente, with an unusual model: every product is supposed to be backed by a peer-reviewed clinical trial.
Flagship products
- Basis — nicotinamide riboside (NR) + pterostilbene to raise NAD+.
- Matter — combination targeting cognitive aging.
- Index — epigenetic-age testing service.
Trial track record
Several RCTs have been published showing that Basis raises blood NAD+ — an intermediate biomarker, not a hard endpoint. Subsequent trials in other indications have had mixed results; the company has positioned trial publication as part of brand identity.
Trade-offs
- Their trials use marker endpoints (NAD+ levels, blood pressure), not long-term healthspan endpoints.
- Cost is significant for compounds available cheaper elsewhere.
- Brand positioning is more scientific-feeling than the typical supplement marketing — this is appealing but should not be confused with hard-endpoint efficacy data.
Why it matters
Elysium represents an attempt to professionalise the longevity-supplement category with academic affiliations and clinical-trial publication. The broader pattern — supplement companies running and publishing trials — is a positive trend even if specific products underwhelm.
- NMN vs NR (NAD+ Precursors) — Comparison.
- NMN vs NR vs Direct NAD+ — Comparison.
- Pterostilbene — Intervention.
- Best Supplements Where Drug Interactions Matter Most — Best-of guide.
- Best Supplements for Longevity (Evidence-Backed Only) — Best-of guide.
Related entries
References
- Martens, C. R. et al. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. Nat. Commun. 9, 1286 (2018).