Ultimate Longevity Bible

Biomarker

DEXA Scan (Body Composition + Bone Density)

Last updated Sun May 17 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

What it is

A low-radiation X-ray (~0.001 mSv) that uses two energy levels to discriminate between fat, lean (muscle + organ + water), and bone. A typical DEXA scan reports:

  • Total and regional lean mass (arms, legs, trunk).
  • Total and regional fat mass.
  • Visceral adipose tissue (VAT) — an estimate, not direct measurement.
  • Bone mineral density (BMD) at hip, spine, and total body.
  • T-score — standard deviations from young-adult mean BMD.

Why it matters

  • Lean mass / appendicular lean mass index (ALMI) — sarcopenia diagnosis and tracking.
  • Visceral fat — the metabolically harmful fat depot; weakly related to BMI.
  • Bone density — osteoporosis screening and treatment monitoring.

T-score interpretation

  • > −1.0: normal.
  • −1.0 to −2.5: osteopenia.
  • < −2.5: osteoporosis.

Frequency

For body composition and longevity tracking, annual scans are typical. For osteoporosis monitoring, every 1–2 years.

Limitations

  • Hydration status modestly affects lean-mass measurement.
  • VAT estimation is less accurate than CT/MRI but adequate for tracking.
  • Cannot distinguish muscle from non-fat lean (water, organ tissue).

Related entries

Sarcopenia, Osteoporosis, Grip strength, VO2max.

References

  • Shepherd, J. A. et al. Body composition by DXA. Bone 104, 101–105 (2017).

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